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Astrid Katzer Selected Research

5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamide

12/2018MEK-inhibitor PD184352 enhances the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922: the role of cell type and drug-irradiation schedule.
6/2016Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
5/2013Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines.
10/2012Hsp90 Inhibitors NVP-AUY922 and NVP-BEP800 May Exert a Significant Radiosensitization on Tumor Cells along with a Cell Type-Specific Cytotoxicity.
4/2012Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia.

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Astrid Katzer Research Topics

Disease

16Neoplasms (Cancer)
04/2019 - 03/2004
15Glioblastoma (Glioblastoma Multiforme)
11/2021 - 03/2008
15Hypoxia (Hypoxemia)
06/2017 - 03/2004
8Carcinoma (Carcinomatosis)
12/2018 - 03/2005
5Fibrosarcoma
04/2011 - 03/2005
4Brain Neoplasms (Brain Tumor)
07/2017 - 01/2010
2Genomic Instability
11/2015 - 04/2013
2Chronic Disease (Chronic Diseases)
07/2013 - 01/2010
2Glioma (Gliomas)
03/2008 - 01/2007
2Head and Neck Neoplasms (Head and Neck Cancer)
08/2006 - 08/2005
1Carcinogenesis
07/2013
1Breast Neoplasms (Breast Cancer)
04/2013
1Neoplasm Metastasis (Metastasis)
01/2010
1Mesothelioma
08/2006
1Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2006

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
04/2019 - 03/2004
5Pharmaceutical PreparationsIBA
12/2018 - 10/2012
55- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
12/2018 - 04/2012
5Messenger RNA (mRNA)IBA
06/2017 - 08/2005
5Carbonic Anhydrase IXIBA
01/2010 - 03/2005
4Oxygen (Dioxygen)IBA
06/2017 - 01/2007
3PI103IBA
11/2021 - 06/2016
3Histones (Histone)IBA
11/2015 - 03/2008
3chetominIBA
07/2013 - 11/2007
3Transcription Factors (Transcription Factor)IBA
01/2010 - 03/2004
3Indicators and Reagents (Reagents)IBA
01/2010 - 08/2006
2DNA (Deoxyribonucleic Acid)IBA
11/2021 - 03/2008
2Radiation-Sensitizing AgentsIBA
12/2018 - 06/2016
2Carbonic Anhydrases (Carbonic Anhydrase)IBA
07/2013 - 01/2010
2Protein Isoforms (Isoforms)IBA
07/2013 - 01/2010
2SulfonamidesIBA
07/2013 - 01/2010
2NVP-BEP800IBA
05/2013 - 10/2012
2Small Interfering RNA (siRNA)IBA
07/2012 - 04/2011
2Glucose (Dextrose)FDA LinkGeneric
07/2007 - 12/2005
2ElementsIBA
07/2007 - 12/2005
2Biomarkers (Surrogate Marker)IBA
01/2007 - 08/2006
2OsteopontinIBA
08/2006 - 08/2005
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
11/2021
1MK 2206IBA
04/2019
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2018
1Carrier Proteins (Binding Protein)IBA
11/2015
1A-Form DNA (A-DNA)IBA
11/2015
1CollagenIBA
01/2015
1matrigelIBA
01/2015
1Carbonic Anhydrase InhibitorsIBA
07/2013
1Acetazolamide (Diamox)FDA LinkGeneric
07/2013
1dactolisibIBA
04/2013
1Cytostatic AgentsIBA
04/2013
1TOR Serine-Threonine KinasesIBA
04/2013
1Phosphotransferases (Kinase)IBA
04/2013
1Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2012
1OligonucleotidesIBA
07/2012
1Bicarbonates (Hydrogen Carbonate)IBA
01/2010
1Carbon DioxideIBA
01/2010
1Protons (Proton)IBA
01/2010
1CamptothecinIBA
03/2008
1Type I DNA Topoisomerases (Topoisomerase I)IBA
03/2008
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
03/2008
1SurvivinIBA
03/2008
1Caspase 3 (Caspase-3)IBA
03/2008
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2007
1Pyruvic Acid (Pyruvate)IBA
07/2007
1Deoxyglucose (2 Deoxy D glucose)IBA
07/2007
1Green Fluorescent ProteinsIBA
07/2007
1EnzymesIBA
01/2007
1Glycoproteins (Glycoprotein)IBA
08/2006
1AsbestosIBA
08/2006
1enhanced green fluorescent proteinIBA
12/2005
1SuspensionsIBA
03/2005

Therapy/Procedure

9Radiotherapy
11/2021 - 03/2004
3Therapeutics
07/2013 - 01/2010
1Aftercare (After-Treatment)
04/2011